Category: Papers

Jana Trifinopoulos
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Cyclin C – a novel therapeutic target for treating B-ALL

Feed-forward (+) and feed-back (-) regulation of IFN response genes
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SFB members review the multilayered transcriptional regulation of interferon-responsive genes

A tailored mouse Paper
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A tailored mouse model for unravelling the development of NK cell malignancy

Targeting STAT5 news
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Targeting STAT5 in hematopoietic cancers

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Vaccine boosts innate immunity in people with dormant immune cells.

Interferons
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Recent Paper: Interferons and stress boost the good and the bad of macrophages

30aniversary
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JAK-STAT 30th Anniversary

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Recent Paper: Antiviral immunity requires changes of chromosome structure

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Recent Paper: Oncogenically mutated TYK2 can be targeted by combinatorial treatment in modelled cell lines and patient-derived cells

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Molecular Pathology and TYK2 Activity During Endotoxin-induced Hyperinflammation

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Distinct Functions of STAT1 Isoforms in NK Cell Maturation and Cytotoxicity

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Therapeutic targeting of STAT3 by monobodies

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Combining the predictive power of deep learning with the interpretability of cell signaling networks

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Comprehensive Analysis of the Chromatin Landscapes of Structural Non-Haematopoietic Cells

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New therapy for aggressive leukemia with poor prognosis

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New findings that are relevant for the treatment of human diseases

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Immune defence and protection of own cells – main regulator of hepatic metabolism identified during infection

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Acute lymphoblastic leukaemia: A new drug class in cancer therapy