Distinct Functions of STAT1 Isoforms in NK Cell Maturation and Cytotoxicity
16. September 2020 2024-10-08 11:41Distinct Functions of STAT1 Isoforms in NK Cell Maturation and Cytotoxicity
Distinct Functions of STAT1 Isoforms in NK Cell Maturation and Cytotoxicity
Using sophisticated genetically engineered mouse models the SFB members Birgit Strobl, Mathias Müller and Veronika Sexl further dissect the NK cell-intrinsic and -extrinsic requirements for STAT1a versus STAT1b in NK cell biology and tumor surveillance.Published in Frontiers in Immunology
Kartin Meissl, Natalija Simonović, Lena Amenitsch, Agnieszka Witalisz-Siepracka, Klara Klein, Caroline Lassnig, Ana Puga, Claus Vogl, Andrea Poelzl, Markus Bosmann, Alexander Dohnal, Veronika Sexl, Mathias Müller & Birgit Strobl
STAT1 isoforms differentially regulate NK cell maturation and anti-tumour activity
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