A tailored mouse model for unravelling the development of NK cell malignancy A consortium supported by the SFB and led by Dagmar Gotthard, Pharmacology and Toxicology Vetmeduni Vienna, developed a NK cell-specific mouse strain carrying a STAT5B gain-of-function mutation. The genetically engineered mice develop a NK cell leukemia closely resembling the respective disease in human […]
A tailored mouse model for unravelling the development of NK cell malignancy
