Natascha Kleiter

Natascha Kleiter,
Section of Translational Cell Genetics,
Medical University Innsbruck

Title: The nuclear orphan receptor NR2F6 as a new cancer immune checkpoint

Natascha Kleiter has characterized NR2F6 as an intracellular immune checkpoint, directly repressing transcription of cytokine genes in T cells relevant for cancer cell rejection and therefore enhancing tumor immune surveillance.